Overview
Nicotinic acetylcholine receptors are ligand-gated ion channels in the nervous system that bind acetylcholine and mediate fast synaptic transmission, playing critical roles in cognitive function, neuromuscular signaling, and various physiological processes. Research published in Neurological Research and Therapy has examined these receptors from multiple perspectives. One study explored the biochemical relationship between kynurenine pathway metabolites and vitamin B6 in the context of diabetes and depression, addressing how alterations in neurotransmitter systems may contribute to comorbid conditions. Another investigation focused on the practical application of spinosad, a pesticide that acts on nicotinic acetylcholine receptors in insects, for managing fruit fly populations in agricultural settings in Sudan. This work demonstrates the receptor's importance as a target for environmentally safer pest control strategies. The topic matters because nicotinic acetylcholine receptors represent key therapeutic and research targets across neurology, psychiatry, and agriculture. Understanding their function in health and disease, as well as their role as sites of pharmacological intervention, has implications for treating neurological disorders, managing psychiatric comorbidities, and developing selective agents for pest management.
Research published in this journal
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Management of Fruit Flies Using Environmentally Safer Pesticide (Spinosad) in Shendi, Sudan
How this research is being cited
The 2 articles above have been cited 32 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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E. A. Ali · 2025 · Egyptian Journal of Desert Research
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2025 · Pharmacological Research
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2024 · Behavioural Brain Research
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2024 · Reproduction
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2023 · Biomedicines
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2023 · Frontiers in Microbiology
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2023 · Cells
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Tryptophan Metabolites as Biomarkers for Esophageal Cancer Susceptibility, Metastasis, and Prognosis2022 · Frontiers in Oncology
A sample of recent works citing this journal's research on Nicotinic Acetylcholine Receptors, linking to each citing work.