A tumour cell is a cell that has acquired genetic and epigenetic alterations enabling abnormal, dysregulated proliferation and evasion of the controls that normally govern cell division, differentiation, and death. Such cells form neoplasms that may be benign or malignant; malignant tumour cells display hallmark cap…
A tumour cell is a cell that has acquired genetic and epigenetic alterations enabling abnormal, dysregulated proliferation and evasion of the controls that normally govern cell division, differentiation, and death. Such cells form neoplasms that may be benign or malignant; malignant tumour cells display hallmark capabilities including sustained proliferative signalling, resistance to apoptosis, replicative immortality, induction of angiogenesis, and the capacity to invade surrounding tissue and metastasise to distant sites. Their behaviour is shaped by driver mutations, altered gene expression, metabolic reprogramming, and interactions with the tumour microenvironment and immune system. Peer-reviewed work relevant to this topic examines the in-vitro properties and evolution of solid human tumour cells, the role of specific genes such as VCAM-1 and CDC6 in tumour formation and senescence, tumour growth dynamics under dietary modulation, inflammatory infiltrate in mammary carcinomas, neoplastic-cell detection in bone marrow, and emerging cell-based therapeutic strategies including engineered T cells. These contributions span cancer cell biology, molecular oncology, and experimental therapeutics, clarifying how malignant cells arise, proliferate, and might be targeted, an area in which the journal publishes peer-reviewed research relevant to cancer.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 51 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Tumor Cell, linking to each citing work.