Ischaemia is the restriction of blood supply to a tissue or organ, producing a shortfall of oxygen and nutrients relative to metabolic demand and, if unresolved, cellular injury and infarction. It most often results from arterial narrowing or occlusion by atherosclerosis, thrombosis, embolism or dissection, and unde…
Ischaemia is the restriction of blood supply to a tissue or organ, producing a shortfall of oxygen and nutrients relative to metabolic demand and, if unresolved, cellular injury and infarction. It most often results from arterial narrowing or occlusion by atherosclerosis, thrombosis, embolism or dissection, and underlies major cardiovascular and cerebrovascular disease. Ischaemic stroke, the most common form of stroke, follows occlusion of a cerebral artery and causes focal neurological deficits, while myocardial ischaemia from coronary artery disease produces angina, infarction and impaired cardiac function; ischaemia–reperfusion injury, in which restoration of flow generates oxidative and inflammatory damage, is a shared mechanism across affected tissues. Diagnosis combines clinical assessment with imaging, electrocardiography and angiography, and management centres on restoring perfusion, limiting injury and preventing recurrence. Research collected under this term reflects both vascular territories: outcomes of percutaneous coronary intervention in ischaemic heart disease, ischaemic stroke from carotid artery dissection, antioxidant and radical-scavenging activity in cardiomyoblast cells, care indicators among stroke inpatients, computed-tomography angiography stroke protocols, endothelial function across stroke subtypes, gene therapy and heart failure, serum calcium and ischaemic-stroke risk, and oxidative stress in experimental ischaemia–reperfusion. The peer-reviewed literature in this area spans cerebral and cardiac ischaemia, their mechanisms, oxidative injury, diagnosis and reperfusion-based management.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 23 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Ischemic, linking to each citing work.