Research Topic · Peer-Reviewed

Alzheimer's Disease

Alzheimer's disease is a progressive neurodegenerative disorder and the most common cause of dementia, characterized clinically by insidious decline in memory, language, executive function, and behaviour. Its neuropathological hallmarks are extracellular plaques of aggregated amyloid-beta peptide and intracellular n…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 33× across the literature 🔖 ISSN 2640-690X 🗓 Reviewed July 2026

Overview

Alzheimer's disease is a progressive neurodegenerative disorder and the most common cause of dementia, characterized clinically by insidious decline in memory, language, executive function, and behaviour. Its neuropathological hallmarks are extracellular plaques of aggregated amyloid-beta peptide and intracellular neurofibrillary tangles of hyperphosphorylated tau protein, accompanied by synaptic loss, neuroinflammation, and progressive neuronal death, particularly in the hippocampus and association cortices. Risk increases markedly with age and is shaped by genetic, vascular, metabolic, and lifestyle factors, and the disease typically advances from a preclinical and mild cognitive impairment stage to overt dementia. In family and primary care, recognition, differentiation from other dementias and from depression, caregiver support, and management of behavioural and psychological symptoms are central, alongside emerging biomarker and imaging approaches for earlier detection. Research relevant to this area examines caregiver knowledge and misconceptions, early prediction through retinal optical coherence tomography imaging, the role of circular RNAs and inflammatory and neuroendocrine markers, distinctions between agitation and aggression in dementia, non-pharmacological management of disrupted sleep, and the interface of cognition with mood and systemic factors. The journal publishes peer-reviewed research relevant to Family Medicine, including the recognition, biomarkers, management, and caregiving dimensions of Alzheimer's disease and related dementias.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2015

Epigenetics and Nutrition

Lundstrom KennethCorresponding author
PanTherapeuitcs, Rue des Remparts 4, CH1095 Lutry, Switzerland
Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603
2021

How this research is being cited

The 12 articles above have been cited 33 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Alzheimer's Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Family Medicine (ISSN 2640-690X).

Journal editorial board
Dr. John P. Bartkowski · United States Dr. Angela Pia Cazzolla · Italy Dr. Ian James Martins · Australia

This page summarises published research for orientation; it is not medical or professional advice.