Overview
Pancreatic cancer is a malignancy arising from the exocrine or, less often, endocrine tissue of the pancreas, with pancreatic ductal adenocarcinoma accounting for the large majority of cases. It is characterized by aggressive biology, early local invasion of adjacent vasculature and bile ducts, and a propensity for distant spread, which together explain its poor prognosis. The clinical course is shaped by late presentation, because early disease is frequently asymptomatic and symptoms such as obstructive jaundice, weight loss, abdominal or back pain, and new-onset diabetes often emerge only once the tumour is advanced. Diagnostic evaluation integrates cross-sectional imaging, tissue sampling, and serum markers, and the comparative value of these markers is an active question: bilirubin and carcinoembryonic antigen, for example, may carry predictive weight alongside or beyond CA 19-9 at initial presentation. Atypical first presentations, including massive upper gastrointestinal haemorrhage from advanced adenocarcinoma, underscore the disease's clinical heterogeneity. Management combines surgical resection in operable cases with chemotherapy and radiotherapy, while supportive concerns such as cancer cachexia and nutritional optimization are integral to care. The journal publishes peer-reviewed research and case studies addressing the presentation, biomarkers, and clinical management of pancreatic malignancy.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Massive Hematemesis as Initial Presentation of Advanced Pancreatic Adenocarcinoma
Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression
Oxidative Telomere Attrition, Nutritional Antioxidants and Biological Aging
Importance of Neutrophil/Lymphocyte Ratio in Squamous-Cell Carcinoma of the Larynx
Drug Design Progress of In silico, In vitro and In vivo Researches
Splenectomy Reports
Complementary and Alternative Treatments for Cancer Prevention and Cure (Part 1)
Beneficial Impacts of Solanum aethiopicum L. in Diabetes Control
Ethics of Modern Stem Cell Research and Therapy: Current Critical and Interdisciplinary Perspectives
Molecular Diagnosis in Clinical Management and Diagnosis of Thyroid Cancer
How this research is being cited
The 12 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2024 · BIO Web of Conferences
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2024 · Nutrients
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2024 · Nutrients
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2024 · BIO Web of Conferences
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2023 · kulak burun boğaz ve baş boyun cerrahisi dergisi
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Jaekwon Seok et al. · 2023 · Journal of Translational Medicine
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2022 · European Archives of Oto-Rhino-Laryngology
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Saptadwipa Ganguly et al. · 2022 · Tumor Suppressor Par-4
A sample of recent works citing this journal's research on Pancreatic Cancer, linking to each citing work.