Research Topic · Peer-Reviewed

Polyacrylamide Gel Electrophoresis

Polyacrylamide gel electrophoresis (PAGE) is a laboratory technique used to separate charged biological molecules, particularly proteins and nucleic acids, according to their size, shape, and charge. Samples are loaded into a gel made of cross-linked polyacrylamide and subjected to an electric field, causing molecul…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 23× across the literature 🔖 ISSN 2692-5915 🗓 Reviewed July 2026

Overview

Polyacrylamide gel electrophoresis (PAGE) is a laboratory technique used to separate charged biological molecules, particularly proteins and nucleic acids, according to their size, shape, and charge. Samples are loaded into a gel made of cross-linked polyacrylamide and subjected to an electric field, causing molecules to migrate through the porous gel matrix at rates determined largely by their molecular size. Variants such as SDS-PAGE denature proteins and coat them with a uniform negative charge so that separation depends chiefly on molecular weight, enabling estimation of size and assessment of purity. PAGE is a fundamental tool in biochemistry, molecular biology, and proteomics, supporting the analysis of protein composition, the characterization of nucleic acids, and applications in research and diagnostics. In forensic and molecular contexts, electrophoretic separation underpins the analysis of biological samples, the study of biomarkers, and the characterization of proteins and DNA. The technique therefore sits within the broad analytical toolkit of Advanced Forensic Sciences, which applies molecular and biochemical methods to the identification and examination of biological evidence and the study of disease-related molecules. This page gathers peer-reviewed, open-access research relevant to molecular and forensic analysis within the broad scope of Advanced Forensic Sciences.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2018

Molecular Biomarkers: A Brief Review

Tarassishin LeonidCorresponding author
 Department of Biological Sciences.
Exact topic Proteomics and Genomics Research doi:10.14302/issn.2326-0793.jpgr-18-2418

How this research is being cited

The 12 articles above have been cited 23 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Polyacrylamide Gel Electrophoresis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Advanced Forensic Sciences (ISSN 2692-5915).

Journal editorial board
Athina Vidaki · Netherlands Timothy Palmbach · United States Ozgur Bulut · Germany

This page summarises published research for orientation; it is not medical or professional advice.