International Journal of Allergy

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International Journal of Allergy-Tropism and Pathogenesis of respiratory virus infection in children - Characterization of Rhinovirus C - Signaling pathway upon infection - Lung injury-CHAN Wan Yi Renee

Assistant Professor, Department of Paediatrics,

The Chinese University of Hong Kong.

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CHAN Wan Yi Renee

Research Interests:

Tropism and Pathogenesis of respiratory virus infection in children
   - Characterization of Rhinovirus C
   - Signaling pathway upon infection
   - Lung injury, regeneration and remodeling 
Virus receptors distribution and its regulation in airways
Rhinovirus epidemiology: Virological and Serological surveillance of rhinovirus in Hong Kong Children

Biography:

  • Dr. Renee WY Chan obtained her PhD degree in the Department of Microbiology and Department of Pathology, The University of Hong Kong and had her post­doctoral fellow training in the Department of Pathology and Centre of Influenza Research, School of Public Health, The University of Hong Kong.
  • She was awarded with the Wong Ching Yee Medical Postgraduate Scholarship and the Research Output Prize of the LKS Faculty of Medicine, HKU, during her PhD study.
  • Since she has started her career in Virology, she has more than 40 publications in international peer­review journals.
  • She has been involved in the discovery of an alternative influenza receptor of avian influenza virus in the human upper respiratory tract (Nature Medicine, 2007) and thereby written a review article on influenza virus receptors (Trends in Microbiology, 2008).
  • With her contribution to the better understanding of influenza virus tropism in human, the Hong Kong Institution of Science awarded her with the Young Scientist Award 2011.
  • In the same year, she received the Young Investigator Award in the XII International Symposium on Respiratory Viral Infections.
  • Her main publications were on risk assessing the emerging viruses, including influenza virus and coronavirus by studying their tissue tropism and pathogenesis in human and swine respiratory organ ex vivo culture models and well­differentiated primary respiratory cell culture models.
  • As a long-term collaboration with St Jude Children’s Research Hospital and The Pulmonary Centre of the Boston University School of Medicine, Dr. Chan attached as Visiting Scientist in Professor Robert Webster’s Laboratory and in Professor Jay Mizgerd’s Laboratory in the fall of 2011, respectively. 
  • Dr Chan has obtained a total of 6 competitive grants (1 GRF and 5 HMRFs) with a total funding amount of over HK$6 million. Dr Chan is also an Academic Editor of the journals: Journal of Virological Methods, PLoS ONE, BioMed Research International, The Scientific World Journal and Journal of Pandemics and Venereal Diseases (Zeal Scienza).